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Latijnse naam: Coriolus versicolor, Tramestes versicolor, Polyporus versicolor

Andere namen: PSK, PSP, VPS, Yun Zhi, Kawaratake, Krestin, Turkey tail (Engels), Schmetterlingstramete (Duits), Tramestes versicolor (Frans), elfenbankje (Nederlands)

Actieve componenten: polysaccharide K (PSK of Krestin), proteïne gebonden polysaccharide petiden (PSP), polysacchariden (betaglucanen 1.3, 1.4 en 1.6), ergosterol deriviaten, tetracyclisch triterpenoïde ergosterol, hydroxymethylquinoline, coriolan 

De coriolus is een paddenstoel die in de volksmond elfenbankje wordt genoemd en groeit ook in de Nederlandse bossen maar wordt niet beschouwd als eetbaar. In de Chinese en Japanse geneeskunde wordt de coriolus al vele duizenden jaren gebruikt als immuunsysteem versterker, heden ten dage is het de meest voorgeschreven paddenstoel met medicinale eigenschappen.

In de jaren '70 heeft de Kureha Chemical Industry Comapny uit Japan de marketing rechten van extracten die zijn haalden uit de coriolus gelicenseerd aan het farmaceutische bedrijf Sankyo Pharmaceutical Company. Het meest bekende product, Krestin genaamd, wordt als geneesmiddel ingezet als niet specifieke immunomodulator bij bepaalde vormen van kanker. De omzet van dit middel bedraagt circa 600 miljoen US dollar op jaarbasis.

Deze paddenstoel kent diverse stoffen met medicinale werking waaronder polysacchariden K (ook wel PSK genoemd)(ref: 1,2,3,6,12,13,24,25 en 27 t/m 32). Er is op dit moment veel wetenschappelijk onderzoek gaande naar de anti kanker eigenschappen van paddenstoelen waaronder dit elfenbankje. Naast deze eigenschappen kent de paddenstoel, net als vele andere, antibacteriële, antivirale en immuunsysteem versterkende effecten. Wel bestaat er kwaliteitsverschil in de extracten (VPS, PSK, PSP), voorschrijven bij bepaalde ziektebeelden moet gebeuren door een deskundige.

Bijwerkingen van het gebruik van coriolus zijn zeldzaam, enige bekende zijn: zwarte ontlasting en donkerkleurende vingernagels.

 

Toepassing Coriolus versicolor in TCM (Traditional Chinese Medicine)
TCM naam Yun zhi (Chinees), kawaratake (Japans)
Smaak Zoet
Werking Milt, hart
Toepassing Licht warm
Bestaand wetenschappelijk onderzoek
Gebied Onderzoek
Afweersysteem 1,2,3,6,7,8,9,11,12,13,14,15,16,19,26,27,28,29,30,31,32
Anti viraal 19,26
Anti tumor/kanker 1 t/m 17,20 t/m 32
Glucose niveau  
Bloeddruk  
Cholesterol  
Ontstekingsremmend 26,27 
Anti coagulantie  
Diabetes  
Leverbescherming  
Allergie  
Longaandoeningen  
Huidproblemen  
Uithoudingsvermogen  

Wetenschappelijk onderzoek Coriolus versicolor - 32 beschikbare referenties

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    18. Ng TB, Chan WY. Polysaccharopeptide from the mushroom Coriolus versicolor possesses analgesic activity but does not produce adverse effects on female reproductive or embryonic development in mice. Gen Pharmacol 1997; 29(2): 269-73. PMID: 9251912
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    23. C. Y. Ho, C. F. Kim, K. N. Leung, K. P. Fung, T. F. Tse, H. Chan and C. B. Lau - Differential anti-tumor activity of coriolus versicolor (Yunzhi) extract through p53- and/or Bcl-2-dependent apoptotic pathway in human breast cancer cells, 2005, Cancer Biol Ther, volume: 4,issue: 6,pages: 638-44 PMID: 15908782
    24. K. Kariya, K. Nakamura, K. Nomoto, S. Matama and K. Saigenji - Mimicking of superoxide dismutase activity by protein-bound polysaccharide of Coriolus versicolor QUEL, and oxidative stress relief for cancer patients, 1992, Mol Biother,volume: 4,issue: 1,pages: 40-6 PMID: 1627273
    25. Y. Kobayashi, K. Kariya, K. Saigenji and K. Nakamura - Enhancement of anti-cancer activity of cisdiaminedichloroplatinum by the protein-bound polysaccharide of Coriolus versicolor QUEL (PS-K) in vitro, 1994, Cancer Biother, volume: 9,issue: 4,pages: 351-8 PMID: 7719382
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    27. Monro, J. - Treatment of Cancer with Mushroom Products, 2003, Archives of Environmental Health, Vol. 58, No. 8 PMID: 15259434
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    29. Kodama Y, Kano T, Tamada R, Kumashiro R, Okamura T, Inokuchi K. Combined effect of prophylactic lymphadenectomy and long term combination chemotherapy for curatively resected carcinoma of the stomach. Jpn J Surg. 1982;12(4):244-8. PMID: 6811786
    30. Nakazato H, Koike A, Saji S, Ogawa N, Sakamoto J. Efficacy of immunochemotherapy as adjuvant treatment after curative resection of gastric cancer. Study Group of Immunochemotherapy with PSK for Gastric Cancer. Lancet. 1994 May 7;343(8906):1122-6. PMID: 7910230
    31. Toi M, Hattori T, Akagi M, Inokuchi K, Orita K, Sugimachi K, Dohi K, Nomura Y, Monden Y, Hamada Y, et al. Randomized adjuvant trial to evaluate the addition of tamoxifen and PSK to chemotherapy in patients with primary breast cancer. 5-Year results from the Nishi-Nippon Group of the Adjuvant Chemoendocrine Therapy for Breast Cancer Organization. Cancer. 1992 Nov 15;70(10):2475-83. PMID: 1423177
    32. Hayakawa K, Mitsuhashi N, Saito Y, Takahashi M, Katano S, Shiojima K, Furuta M, Niibe H. Effect of krestin (PSK) as adjuvant treatment on the prognosis after radical radiotherapy in patients with non-small cell lung cancer. Anticancer Res. 1993 Sep-Oct;13(5C):1815-20. PMID: 8267386